Collagen Peptides Clinical Studies

Hydrolyzed Collagen Clinically Studied with Proven Results.

60+ clinical published studies on hydrolyzed collagen (footnote 1)

>90% Absorption rate

>78% Increase in dermis density (footnote3)

>30% Decrease in deep wrinkles formation. (footnote4)

Collagen Peptides Clinical Studies on Skin

1. An Overview of the Beneficial Effects of Hydrolysed Collagen supplements as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies Sibilla S, Godfrey M et al, , London UK.3Dr. Anil Anti-Ageing and Parkfield Medical Centre, Birmingham, UK. The Open Nutraceuticals Journal, 2015, 8, 29-42.


2.The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: J Cosmet Dermatol. 2015 Dec;14(4):291-301. doi: 10.1111/jocd.12174. Epub 2015 Sep 12. http://www.ncbi.nlm.nih.gov/pubmed/26362110

3. Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study Proksch E et al., Dept. of Dermatology, University of Kiel, Kiel, Germany. Skin Pharmacol Phy., Aug. 2013; 27(1):47-55.

4. Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts Ohara H et al., Food and Health R&D Laboratories, Meiji Seika Kaisha, Saitama, Japan. Journal of Dermatology, 2010 Apr; 37(4):330-8.

5. Effects of Sizes and Conformations of Fish-Scale Collagen Peptides on Facial Skin Qualities and Transdermal Penetration Efficiency Huey-Jine Chai et al., Dept. of Food Science, National Taiwan Ocean University, Keelung, Taiwan. Journal of Biomedicine and Biotechnology, Vol. 2010.

6. Collagen Hydrolysate Intake Increases Skin Collagen Expression and Suppresses Matrix Metalloproteinase 2 Activity JOURNAL OF MEDICINAL FOOD J Med Food 14 (6) 2011, 618–624

7. Clinical Effects of Fish Type I collagen hydrolysate on skin properties
Hitoshi Matsumoto, et al., ITE Letters on batteries, new technologies and medicine, 2006.

8. Effects of Ingestion of Collagen Peptide on Collagen Fibrils and Glycosaminoglycans in Achilles tendon
Minaguchi Jun (Rakuno Gakuen University, Hokkaido, Japan) et al., 2005.

9. Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates
Iwai K et al, Kyoto Prefectural University, Japan. Journal of Agricultural Food Chemistry, 2005 Aug 10; 53(16):6531-6.

10. Effect of the Collagen Peptide Drinks on the Elastic Properties of Facial Skin in Normal Volunteers Hayamizu Kosuke et al. Journal of New Remedies & Clinics, Japan, 2000; 49-9:867-873.

11. Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis a Department of Dermatology, University of Kiel, and b Collagen Research Institute, Kiel , and c Skin Investigation and
Technology, Hamburg , Germany;


(1) An Overview of the Beneficial Effects of Hydrolyzed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies; The Open Nutraceutical Journal, 2015; 8: 29-42.
(2) Oral Administration of (14)C Labeled Gelatin Hydrolysate Leads to an Accumulation of Radioactivity in Cartilage of Mice; Journal of Nutrition, 1999; 129(10): 1891-5.
(3) A Novel Micronutrient Supplement in Skin Aging: A Randomized Placebo-controlled Double-blind Study; Journal of Cosmetic Dermatology, 2005; 4
(4): 277-84. (4) Hydrolyzed Collagen & Skin Health Study YNTKK – 2008; Rousselot, France Anti-aging; 2009 corporate publication.

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